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Differentiation-dependent photodynamic therapy regulated by porphobilinogen deaminase in B16 melanoma
Protoporphyrin IX (PpIX) synthesis by malignant cells is clinically exploited for photodiagnosis and photodynamic therapy following administration of 5-aminolevulinic acid (ALA). The expression and activity of the housekeeping porphobilinogen deaminase (PBGD) was correlated to PpIX synthesis in diff...
Autores principales: | Ickowicz Schwartz, D, Gozlan, Y, Greenbaum, L, Babushkina, T, Katcoff, D J, Malik, Z |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409749/ https://www.ncbi.nlm.nih.gov/pubmed/15150593 http://dx.doi.org/10.1038/sj.bjc.6601760 |
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