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Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor α
The pro-peptide of transforming growth factor α (proTGFα) was recently found in hepatocyte nuclei preparing for DNA replication, which suggests a role of nuclear proTGFα for mitogenic signalling. This study investigates whether the nuclear occurrence of the pro-peptide is involved in the altered gro...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409777/ https://www.ncbi.nlm.nih.gov/pubmed/15534611 http://dx.doi.org/10.1038/sj.bjc.6602191 |