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Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers

In Drosophila, the Slit gene product, a secreted glycoprotein, acts as a midline repellent to guide axonal development during embryogenesis. Three human Slit gene orthologues have been characterised and recently we reported frequent promoter region hypermethylation and transcriptional silencing of S...

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Detalles Bibliográficos
Autores principales: Dickinson, R E, Dallol, A, Bieche, I, Krex, D, Morton, D, Maher, E R, Latif, F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409788/
https://www.ncbi.nlm.nih.gov/pubmed/15534609
http://dx.doi.org/10.1038/sj.bjc.6602222