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Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers
In Drosophila, the Slit gene product, a secreted glycoprotein, acts as a midline repellent to guide axonal development during embryogenesis. Three human Slit gene orthologues have been characterised and recently we reported frequent promoter region hypermethylation and transcriptional silencing of S...
Autores principales: | Dickinson, R E, Dallol, A, Bieche, I, Krex, D, Morton, D, Maher, E R, Latif, F |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409788/ https://www.ncbi.nlm.nih.gov/pubmed/15534609 http://dx.doi.org/10.1038/sj.bjc.6602222 |
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