The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer

The relationship between tumour stage, T-lymphocyte subset infiltration and survival was examined in patients with prostate cancer (n=80). On multivariate analysis PSA (HR 2.47, 95% CI 1.27–4.83, P=0.008) and CD4+ T-lymphocyte count (HR 2.29, 95% CI 1.25–4.22, P=0.008) had independent significance....

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Detalles Bibliográficos
Autores principales: McArdle, P A, Canna, K, McMillan, D C, McNicol, A-M, Campbell, R, Underwood, M A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409839/
https://www.ncbi.nlm.nih.gov/pubmed/15266325
http://dx.doi.org/10.1038/sj.bjc.6601943
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author McArdle, P A
Canna, K
McMillan, D C
McNicol, A-M
Campbell, R
Underwood, M A
author_facet McArdle, P A
Canna, K
McMillan, D C
McNicol, A-M
Campbell, R
Underwood, M A
author_sort McArdle, P A
collection PubMed
description The relationship between tumour stage, T-lymphocyte subset infiltration and survival was examined in patients with prostate cancer (n=80). On multivariate analysis PSA (HR 2.47, 95% CI 1.27–4.83, P=0.008) and CD4+ T-lymphocyte count (HR 2.29, 95% CI 1.25–4.22, P=0.008) had independent significance. Increased CD4+ T-lymphocyte infiltration within the tumour was stage independent and associated with poor outcome in patients with prostate cancer.
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spelling pubmed-24098392009-09-10 The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer McArdle, P A Canna, K McMillan, D C McNicol, A-M Campbell, R Underwood, M A Br J Cancer Short Communication The relationship between tumour stage, T-lymphocyte subset infiltration and survival was examined in patients with prostate cancer (n=80). On multivariate analysis PSA (HR 2.47, 95% CI 1.27–4.83, P=0.008) and CD4+ T-lymphocyte count (HR 2.29, 95% CI 1.25–4.22, P=0.008) had independent significance. Increased CD4+ T-lymphocyte infiltration within the tumour was stage independent and associated with poor outcome in patients with prostate cancer. Nature Publishing Group 2004-08-02 2004-07-13 /pmc/articles/PMC2409839/ /pubmed/15266325 http://dx.doi.org/10.1038/sj.bjc.6601943 Text en Copyright © 2004 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Short Communication
McArdle, P A
Canna, K
McMillan, D C
McNicol, A-M
Campbell, R
Underwood, M A
The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer
title The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer
title_full The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer
title_fullStr The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer
title_full_unstemmed The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer
title_short The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer
title_sort relationship between t-lymphocyte subset infiltration and survival in patients with prostate cancer
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409839/
https://www.ncbi.nlm.nih.gov/pubmed/15266325
http://dx.doi.org/10.1038/sj.bjc.6601943
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