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An antagonist of retinoic acid receptors more effectively inhibits growth of human prostate cancer cells than normal prostate epithelium

Screening of synthetic retinoids for activity against prostate carcinoma cell lines has identified antagonists of retinoic acid receptors (RARs) as potent growth inhibitors (Hammond et al, 2001, Br J Cancer 85, 453–462). Here we report that 5 days of exposure to a high-affinity pan-RAR antagonist (A...

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Detalles Bibliográficos
Autores principales:	Keedwell, R G, Zhao, Y, Hammond, L A, Wen, K, Qin, S, Atangan, L I, Shurland, D-L, Wallace, D M A, Bird, R, Reitmair, A, Chandraratna, R A S, Brown, G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2004
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409843/ https://www.ncbi.nlm.nih.gov/pubmed/15266311 http://dx.doi.org/10.1038/sj.bjc.6602024

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