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High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma
Telomerase, an enzyme related with cellular immortality, has been extensively studied in many kinds of malignant tumours for clinical diagnostic or prognostic utilities. Telomerase activity is mainly regulated by the expression of hTERT (human telomerase reverse transcriptase), which is a catalytic...
Autores principales: | Hiyama, E, Yamaoka, H, Matsunaga, T, Hayashi, Y, Ando, H, Suita, S, Horie, H, Kaneko, M, Sasaki, F, Hashizume, K, Nakagawara, A, Ohnuma, N, Yokoyama, T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409875/ https://www.ncbi.nlm.nih.gov/pubmed/15280920 http://dx.doi.org/10.1038/sj.bjc.6602054 |
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