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The risk and prognosis of cancer after hospitalisation for herpes zoster: a population-based follow-up study

We examined the risk of cancer and survival in a cohort of patients hospitalised with herpes zoster between 1977 and 1996, drawn from the Danish National Registry of Patients. Through linkage with the Danish Cancer Registry, we compared the observed number of cancers with the expected number on the...

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Autores principales: Sørensen, H T, Olsen, J H, Jepsen, P, Johnsen, S P, Schønheyder, H C, Mellemkjær, L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409892/
https://www.ncbi.nlm.nih.gov/pubmed/15328522
http://dx.doi.org/10.1038/sj.bjc.6602120
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author Sørensen, H T
Olsen, J H
Jepsen, P
Johnsen, S P
Schønheyder, H C
Mellemkjær, L
author_facet Sørensen, H T
Olsen, J H
Jepsen, P
Johnsen, S P
Schønheyder, H C
Mellemkjær, L
author_sort Sørensen, H T
collection PubMed
description We examined the risk of cancer and survival in a cohort of patients hospitalised with herpes zoster between 1977 and 1996, drawn from the Danish National Registry of Patients. Through linkage with the Danish Cancer Registry, we compared the observed number of cancers with the expected number on the basis of national age-, gender-, and site-specific incidence rates. The survival of herpes zoster patients with cancer was compared with that of non-herpes zoster patients with cancer. Among the 10 588 patients hospitalised with herpes zoster whom we identified, 1427 cancers were observed compared with 1239 expected (relative risk=1.2, 95% confidence interval 1.1–1.2). The risk was substantially elevated during the first year of follow-up, mainly for haematological cancer. Patients with cancer within 1 year of follow-up had a higher prevalence of distant metastases than controls, although the mortality was similar. For those with haematological cancer, however, the mortality was higher for herpes zoster patients than for controls. Haematological cancer following hospitalisation for herpes zoster has a poorer prognosis than in non-herpes zoster patients.
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spelling pubmed-24098922009-09-10 The risk and prognosis of cancer after hospitalisation for herpes zoster: a population-based follow-up study Sørensen, H T Olsen, J H Jepsen, P Johnsen, S P Schønheyder, H C Mellemkjær, L Br J Cancer Epidemiology We examined the risk of cancer and survival in a cohort of patients hospitalised with herpes zoster between 1977 and 1996, drawn from the Danish National Registry of Patients. Through linkage with the Danish Cancer Registry, we compared the observed number of cancers with the expected number on the basis of national age-, gender-, and site-specific incidence rates. The survival of herpes zoster patients with cancer was compared with that of non-herpes zoster patients with cancer. Among the 10 588 patients hospitalised with herpes zoster whom we identified, 1427 cancers were observed compared with 1239 expected (relative risk=1.2, 95% confidence interval 1.1–1.2). The risk was substantially elevated during the first year of follow-up, mainly for haematological cancer. Patients with cancer within 1 year of follow-up had a higher prevalence of distant metastases than controls, although the mortality was similar. For those with haematological cancer, however, the mortality was higher for herpes zoster patients than for controls. Haematological cancer following hospitalisation for herpes zoster has a poorer prognosis than in non-herpes zoster patients. Nature Publishing Group 2004-10-04 2004-08-24 /pmc/articles/PMC2409892/ /pubmed/15328522 http://dx.doi.org/10.1038/sj.bjc.6602120 Text en Copyright © 2004 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Epidemiology
Sørensen, H T
Olsen, J H
Jepsen, P
Johnsen, S P
Schønheyder, H C
Mellemkjær, L
The risk and prognosis of cancer after hospitalisation for herpes zoster: a population-based follow-up study
title The risk and prognosis of cancer after hospitalisation for herpes zoster: a population-based follow-up study
title_full The risk and prognosis of cancer after hospitalisation for herpes zoster: a population-based follow-up study
title_fullStr The risk and prognosis of cancer after hospitalisation for herpes zoster: a population-based follow-up study
title_full_unstemmed The risk and prognosis of cancer after hospitalisation for herpes zoster: a population-based follow-up study
title_short The risk and prognosis of cancer after hospitalisation for herpes zoster: a population-based follow-up study
title_sort risk and prognosis of cancer after hospitalisation for herpes zoster: a population-based follow-up study
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409892/
https://www.ncbi.nlm.nih.gov/pubmed/15328522
http://dx.doi.org/10.1038/sj.bjc.6602120
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