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Pharmacokinetics of the nonsteroidal steroid sulphatase inhibitor 667 COUMATE and its sequestration into red blood cells in rats
Breast cancer is a major cause of mortality in Western countries and there is an urgent requirement for novel treatment strategies. The nonsteroidal sulphatase inhibitor 667 COUMATE inhibits hepatic steroid sulphatase and growth of oestrone sulphate stimulated tumours in the nitrosomethylurea-induce...
Autores principales: | Ireson, C R, Chander, S K, Purohit, A, Parish, D C, Woo, L W L, Potter, B V L, Reed, M J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409900/ https://www.ncbi.nlm.nih.gov/pubmed/15328524 http://dx.doi.org/10.1038/sj.bjc.6602130 |
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