Cargando…
Analysis of resveratrol as a lung cancer chemopreventive agent in A/J mice exposed to benzo[a]pyrene
Resveratrol inhibits PAH bioactivation through reduced expression of the CYP1A1 and CYP1B1 genes in human bronchial epithelial cells. Ad libitum access to a diet containing resveratrol showed no effect on benzo[a]pyrene-induced lung tumorigenesis in A/J mice. Also, resveratrol did not change CYP1A1...
Autores principales: | Berge, G, Øvrebø, S, Eilertsen, E, Haugen, A, Mollerup, S |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409901/ https://www.ncbi.nlm.nih.gov/pubmed/15316568 http://dx.doi.org/10.1038/sj.bjc.6602125 |
Ejemplares similares
-
Resveratrol inhibits benzo[a]pyrene–DNA adduct formation in human bronchial epithelial cells
por: Berge, G, et al.
Publicado: (2004) -
Fertility in mice after prenatal exposure to benzo[a]pyrene and inorganic lead.
por: Kristensen, P, et al.
Publicado: (1995) -
Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4′-tetramethoxystilbene
por: Sale, S, et al.
Publicado: (2004) -
Characterisation of metabolites of the putative cancer chemopreventive agent quercetin and their effect on cyclo-oxygenase activity
por: Jones, D J L, et al.
Publicado: (2004) -
The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1
por: Potter, G A, et al.
Publicado: (2002)