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Bax regulates c-Myc-induced mammary tumour apoptosis but not proliferation in MMTV-c-myc transgenic mice

The expression of the proto-oncogene c-myc is frequently deregulated, via multiple mechanisms, in human breast cancers. Deregulated expression of c-myc contributes to mammary epithelial cell transformation and is causally involved in mammary tumorigenesis in MMTV-c-myc transgenic mice. c-Myc is know...

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Detalles Bibliográficos
Autores principales:	Jamerson, M H, Johnson, M D, Korsmeyer, S J, Furth, P A, Dickson, R B
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2004
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409914/ https://www.ncbi.nlm.nih.gov/pubmed/15354213 http://dx.doi.org/10.1038/sj.bjc.6602137

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