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Proteomic Analysis of Ovarian Cancer Cells Reveals Dynamic Processes of Protein Secretion and Shedding of Extra-Cellular Domains
BACKGROUND: Elucidation of the repertoire of secreted and cell surface proteins of tumor cells is relevant to molecular diagnostics, tumor imaging and targeted therapies. We have characterized the cell surface proteome and the proteins released into the extra-cellular milieu of three ovarian cancer...
Autores principales: | Faça, Vitor M., Ventura, Aviva P., Fitzgibbon, Mathew P., Pereira-Faça, Sandra R., Pitteri, Sharon J., Green, Ann E., Ireton, Renee C., Zhang, Qing, Wang, Hong, O'Briant, Kathy C., Drescher, Charles W., Schummer, Michèl, McIntosh, Martin W., Knudsen, Beatrice S., Hanash, Samir M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409963/ https://www.ncbi.nlm.nih.gov/pubmed/18560578 http://dx.doi.org/10.1371/journal.pone.0002425 |
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