A Drastic Reduction in the Life Span of Cystatin C L68Q Carriers Due to Life-Style Changes during the Last Two Centuries

Hereditary cystatin C amyloid angiopathy (HCCAA) is an autosomal dominant disease with high penetrance, manifest by brain hemorrhages in young normotensive adults. In Iceland, this condition is caused by the L68Q mutation in the cystatin C gene, with contemporary carriers reaching an average age of...

Descripción completa

Detalles Bibliográficos
Autores principales: Palsdottir, Astridur, Helgason, Agnar, Palsson, Snaebjorn, Bjornsson, Hans Tomas, Bragason, Birkir Thor, Gretarsdottir, Solveig, Thorsteinsdottir, Unnur, Olafsson, Elias, Stefansson, Kari
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2409978/
https://www.ncbi.nlm.nih.gov/pubmed/18566660
http://dx.doi.org/10.1371/journal.pgen.1000099

Ejemplares similares

Ejemplares similares