Development of spontaneous tumours and intestinal lesions in Fhit gene knockout mice

The fragile histidine triad (FHIT) gene is frequently inactivated in various types of tumours. However, the system-wide pathology caused by FHIT inactivation has not been examined in detail. Here we demonstrate that Fhit gene knockout mice develop tumours in the lymphoid tissue, liver, uterus, testi...

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Detalles Bibliográficos
Autores principales: Fujishita, T, Doi, Y, Sonoshita, M, Hiai, H, Oshima, M, Huebner, K, Croce, C M, Taketo, M M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410018/
https://www.ncbi.nlm.nih.gov/pubmed/15467769
http://dx.doi.org/10.1038/sj.bjc.6602182

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