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Fhit-deficient normal and cancer cells are mitomycin C and UVC resistant

To identify functions of the fragile tumour suppressor gene, FHIT, matched pairs of Fhit-negative and -positive human cancer cell clones, and normal cell lines established from Fhit −/− and +/+ mice, were stressed and examined for differences in cell cycle kinetics and survival. A larger fraction of...

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Detalles Bibliográficos
Autores principales:	Ottey, M, Han, S-Y, Druck, T, Barnoski, B L, McCorkell, K A, Croce, C M, Raventos-Suarez, C, Fairchild, C R, Wang, Y, Huebner, K
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2004
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410021/ https://www.ncbi.nlm.nih.gov/pubmed/15494723 http://dx.doi.org/10.1038/sj.bjc.6602058

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