Clusterin overexpression in both malignant and nonmalignant prostate epithelial cells induces cell cycle arrest and apoptosis

Expression of the castration-induced clusterin protein is incompatible with the survival of human prostate cancer cells in tissues and in cell culture. To investigate the fate of human prostate epithelial cells, when engineered to maintain expression of clusterin protein, we have used an IRES-hyg ve...

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Detalles Bibliográficos
Autores principales: Scaltriti, M, Bettuzzi, S, Sharrard, R M, Caporali, A, Caccamo, A E, Maitland, N J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410047/
https://www.ncbi.nlm.nih.gov/pubmed/15494717
http://dx.doi.org/10.1038/sj.bjc.6602193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410047/
https://www.ncbi.nlm.nih.gov/pubmed/15494717
http://dx.doi.org/10.1038/sj.bjc.6602193

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