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Clusterin overexpression in both malignant and nonmalignant prostate epithelial cells induces cell cycle arrest and apoptosis
Expression of the castration-induced clusterin protein is incompatible with the survival of human prostate cancer cells in tissues and in cell culture. To investigate the fate of human prostate epithelial cells, when engineered to maintain expression of clusterin protein, we have used an IRES-hyg ve...
Autores principales: | Scaltriti, M, Bettuzzi, S, Sharrard, R M, Caporali, A, Caccamo, A E, Maitland, N J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410047/ https://www.ncbi.nlm.nih.gov/pubmed/15494717 http://dx.doi.org/10.1038/sj.bjc.6602193 |
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