Public Databases and Software for the Pathway Analysis of Cancer Genomes

The study of pathway disruption is key to understanding cancer biology. Advances in high throughput technologies have led to the rapid accumulation of genomic data. The explosion in available data has generated opportunities for investigation of concerted changes that disrupt biological functions, t...

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Detalles Bibliográficos
Autores principales: Tsui, Ivy F.L., Chari, Raj, Buys, Timon P.H., Lam, Wan L.
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2007
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410087/
https://www.ncbi.nlm.nih.gov/pubmed/19455256
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author Tsui, Ivy F.L.
Chari, Raj
Buys, Timon P.H.
Lam, Wan L.
author_facet Tsui, Ivy F.L.
Chari, Raj
Buys, Timon P.H.
Lam, Wan L.
author_sort Tsui, Ivy F.L.
collection PubMed
description The study of pathway disruption is key to understanding cancer biology. Advances in high throughput technologies have led to the rapid accumulation of genomic data. The explosion in available data has generated opportunities for investigation of concerted changes that disrupt biological functions, this in turns created a need for computational tools for pathway analysis. In this review, we discuss approaches to the analysis of genomic data and describe the publicly available resources for studying biological pathways.
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spelling pubmed-24100872009-11-10 Public Databases and Software for the Pathway Analysis of Cancer Genomes Tsui, Ivy F.L. Chari, Raj Buys, Timon P.H. Lam, Wan L. Cancer Inform Original Research The study of pathway disruption is key to understanding cancer biology. Advances in high throughput technologies have led to the rapid accumulation of genomic data. The explosion in available data has generated opportunities for investigation of concerted changes that disrupt biological functions, this in turns created a need for computational tools for pathway analysis. In this review, we discuss approaches to the analysis of genomic data and describe the publicly available resources for studying biological pathways. Libertas Academica 2007-12-12 /pmc/articles/PMC2410087/ /pubmed/19455256 Text en © 2007 The authors. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Original Research
Tsui, Ivy F.L.
Chari, Raj
Buys, Timon P.H.
Lam, Wan L.
Public Databases and Software for the Pathway Analysis of Cancer Genomes
title Public Databases and Software for the Pathway Analysis of Cancer Genomes
title_full Public Databases and Software for the Pathway Analysis of Cancer Genomes
title_fullStr Public Databases and Software for the Pathway Analysis of Cancer Genomes
title_full_unstemmed Public Databases and Software for the Pathway Analysis of Cancer Genomes
title_short Public Databases and Software for the Pathway Analysis of Cancer Genomes
title_sort public databases and software for the pathway analysis of cancer genomes
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410087/
https://www.ncbi.nlm.nih.gov/pubmed/19455256
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