Pharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents

2-Methoxyoestradiol (2-MeOE2) is an endogenous oestrogen metabolite that inhibits the proliferation of cancer cells in vitro, and it is also antiangiogenic. In vivo 2-MeOE2, when administered at relatively high doses, inhibits the growth of tumours derived from breast cancer cells, sarcomas and mela...

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Detalles Bibliográficos
Autores principales: Ireson, C R, Chander, S K, Purohit, A, Perera, S, Newman, S P, Parish, D, Leese, M P, Smith, A C, Potter, B V L, Reed, M J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410173/
https://www.ncbi.nlm.nih.gov/pubmed/14970876
http://dx.doi.org/10.1038/sj.bjc.6601591

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