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Tumour-derived TGF-β1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells

The development of an altered stromal microenvironment is a common feature of many tumours including squamous cell carcinoma (SCC), and there is increasing evidence that these changes in the stroma, which include increased expression of proteases and cytokines, may actually promote tumour progressio...

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Detalles Bibliográficos
Autores principales: Lewis, M P, Lygoe, K A, Nystrom, M L, Anderson, W P, Speight, P M, Marshall, J F, Thomas, G J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410183/
https://www.ncbi.nlm.nih.gov/pubmed/14970860
http://dx.doi.org/10.1038/sj.bjc.6601611

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