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3-D structure of extracellular matrix regulates gene expression in cultured hepatic stellate cells to induce process elongation

HSCs showed myofibroblast-like shapes when cultured on polystyrene surface or on type I collagen-coated surface, whereas HSCs cultured on type I collagen gel were induced to elongate cellular processes, suggesting that HSCs recognize 3-D structure of extracellular type I collagen fibrils and change...

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Detalles Bibliográficos
Autores principales:	Sato, Mitsuru, Sato, Takeya, Kojima, Naosuke, Imai, Katsuyuki, Higashi, Nobuyo, Wang, Da-Ren, Senoo, Haruki
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410227/ https://www.ncbi.nlm.nih.gov/pubmed/14960156 http://dx.doi.org/10.1186/1476-5926-2-S1-S4

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