Genetic and epigenetic analyses of MBD3 in colon and lung cancer

MBD3 is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alterat...

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Detalles Bibliográficos
Autores principales: Zhu, Y, Harrison, D J, Bader, S A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410281/
https://www.ncbi.nlm.nih.gov/pubmed/15138480
http://dx.doi.org/10.1038/sj.bjc.6601776
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author Zhu, Y
Harrison, D J
Bader, S A
author_facet Zhu, Y
Harrison, D J
Bader, S A
author_sort Zhu, Y
collection PubMed
description MBD3 is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alteration in these cancers.
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spelling pubmed-24102812009-09-10 Genetic and epigenetic analyses of MBD3 in colon and lung cancer Zhu, Y Harrison, D J Bader, S A Br J Cancer Genetics and Genomics MBD3 is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alteration in these cancers. Nature Publishing Group 2004-05-17 2004-04-13 /pmc/articles/PMC2410281/ /pubmed/15138480 http://dx.doi.org/10.1038/sj.bjc.6601776 Text en Copyright © 2004 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Genetics and Genomics
Zhu, Y
Harrison, D J
Bader, S A
Genetic and epigenetic analyses of MBD3 in colon and lung cancer
title Genetic and epigenetic analyses of MBD3 in colon and lung cancer
title_full Genetic and epigenetic analyses of MBD3 in colon and lung cancer
title_fullStr Genetic and epigenetic analyses of MBD3 in colon and lung cancer
title_full_unstemmed Genetic and epigenetic analyses of MBD3 in colon and lung cancer
title_short Genetic and epigenetic analyses of MBD3 in colon and lung cancer
title_sort genetic and epigenetic analyses of mbd3 in colon and lung cancer
topic Genetics and Genomics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410281/
https://www.ncbi.nlm.nih.gov/pubmed/15138480
http://dx.doi.org/10.1038/sj.bjc.6601776
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AT badersa geneticandepigeneticanalysesofmbd3incolonandlungcancer

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