Role of infiltrated leucocytes in tumour growth and spread

Leucocytes are a major component of the tumour microenvironment. Recent studies have indicated that the infiltration and activity of these host cells are regulated by the tumour to promote its survival and progression. Through the production of an array of growth factors, proteases and angiogenic me...

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Detalles Bibliográficos
Autores principales: Lin, E Y, Pollard, J W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410285/
https://www.ncbi.nlm.nih.gov/pubmed/15164120
http://dx.doi.org/10.1038/sj.bjc.6601705
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author Lin, E Y
Pollard, J W
author_facet Lin, E Y
Pollard, J W
author_sort Lin, E Y
collection PubMed
description Leucocytes are a major component of the tumour microenvironment. Recent studies have indicated that the infiltration and activity of these host cells are regulated by the tumour to promote its survival and progression. Through the production of an array of growth factors, proteases and angiogenic mediators, leucocytes in the tumour microenvironment promote tumour growth, angiogenesis and metastasis.
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spelling pubmed-24102852009-09-10 Role of infiltrated leucocytes in tumour growth and spread Lin, E Y Pollard, J W Br J Cancer Minireview Leucocytes are a major component of the tumour microenvironment. Recent studies have indicated that the infiltration and activity of these host cells are regulated by the tumour to promote its survival and progression. Through the production of an array of growth factors, proteases and angiogenic mediators, leucocytes in the tumour microenvironment promote tumour growth, angiogenesis and metastasis. Nature Publishing Group 2004-06-01 2004-03-30 /pmc/articles/PMC2410285/ /pubmed/15164120 http://dx.doi.org/10.1038/sj.bjc.6601705 Text en Copyright © 2004 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Lin, E Y
Pollard, J W
Role of infiltrated leucocytes in tumour growth and spread
title Role of infiltrated leucocytes in tumour growth and spread
title_full Role of infiltrated leucocytes in tumour growth and spread
title_fullStr Role of infiltrated leucocytes in tumour growth and spread
title_full_unstemmed Role of infiltrated leucocytes in tumour growth and spread
title_short Role of infiltrated leucocytes in tumour growth and spread
title_sort role of infiltrated leucocytes in tumour growth and spread
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410285/
https://www.ncbi.nlm.nih.gov/pubmed/15164120
http://dx.doi.org/10.1038/sj.bjc.6601705
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