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Escalating Plasmodium falciparum antifolate drug resistance mutations in Macha, rural Zambia

BACKGROUND: In Zambia the first-line treatment for uncomplicated malaria is artemisinin combination therapy (ACT), with artemether-lumefantrine currently being used. However, the antifolate regimen, sulphadoxine-pyrimethamine (SP), remains the treatment of choice in children weighing less than 5 kg...

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Detalles Bibliográficos
Autores principales:	Mkulama, Mtawa AP, Chishimba, Sandra, Sikalima, Jay, Rouse, Petrica, Thuma, Philip E, Mharakurwa, Sungano
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2412897/ https://www.ncbi.nlm.nih.gov/pubmed/18495008 http://dx.doi.org/10.1186/1475-2875-7-87

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