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Proteasomal degradation restricts the nuclear lifespan of AID

Activation-induced cytidine deaminase (AID) initiates all postrearrangement processes that diversify the immunoglobulin repertoire by specific deamination of cytidines at the immunoglobulin (Ig) locus. As uncontrolled expression of AID is potentially mutagenic, different types of regulation, particu...

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Detalles Bibliográficos
Autores principales:	Aoufouchi, Said, Faili, Ahmad, Zober, Carole, D'Orlando, Orietta, Weller, Sandra, Weill, Jean-Claude, Reynaud, Claude-Agnès
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413033/ https://www.ncbi.nlm.nih.gov/pubmed/18474627 http://dx.doi.org/10.1084/jem.20070950

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