Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity

BACKGROUND: Inflammation plays an important role in the pathogenesis of Parkinson's disease (PD) through over-activation of microglia, which consequently causes the excessive production of proinflammatory and neurotoxic factors, and impacts surrounding neurons and eventually induces neurodegene...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Dan, Hu, Xiaoming, Wei, Sung-Jen, Liu, Jie, Gao, Huiming, Qian, Li, Wilson, Belinda, Liu, Gengtao, Hong, Jau-Shyong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413210/
https://www.ncbi.nlm.nih.gov/pubmed/18507839
http://dx.doi.org/10.1186/1742-2094-5-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413210/
https://www.ncbi.nlm.nih.gov/pubmed/18507839
http://dx.doi.org/10.1186/1742-2094-5-21

Ejemplares similares