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Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity
BACKGROUND: Inflammation plays an important role in the pathogenesis of Parkinson's disease (PD) through over-activation of microglia, which consequently causes the excessive production of proinflammatory and neurotoxic factors, and impacts surrounding neurons and eventually induces neurodegene...
Autores principales: | Zhang, Dan, Hu, Xiaoming, Wei, Sung-Jen, Liu, Jie, Gao, Huiming, Qian, Li, Wilson, Belinda, Liu, Gengtao, Hong, Jau-Shyong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413210/ https://www.ncbi.nlm.nih.gov/pubmed/18507839 http://dx.doi.org/10.1186/1742-2094-5-21 |
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