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Erwin Schroedinger, Francis Crick and epigenetic stability
Schroedinger's book 'What is Life?' is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and systems biology. I contrast two classes of potentia...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413215/ https://www.ncbi.nlm.nih.gov/pubmed/18419815 http://dx.doi.org/10.1186/1745-6150-3-15 |
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author | Ogryzko, Vasily V |
author_facet | Ogryzko, Vasily V |
author_sort | Ogryzko, Vasily V |
collection | PubMed |
description | Schroedinger's book 'What is Life?' is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and systems biology. I contrast two classes of potential mechanisms of epigenetic stability: 'epigenetic templating' and 'systems biology' approaches, and consider them from the point of view expressed by Schroedinger. I also discuss how quantum entanglement, a nonclassical feature of quantum mechanics, can help to address the 'problem of small numbers' that led Schroedinger to promote the idea of a molecular code-script for explaining the stability of biological order. |
format | Text |
id | pubmed-2413215 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-24132152008-06-06 Erwin Schroedinger, Francis Crick and epigenetic stability Ogryzko, Vasily V Biol Direct Hypothesis Schroedinger's book 'What is Life?' is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and systems biology. I contrast two classes of potential mechanisms of epigenetic stability: 'epigenetic templating' and 'systems biology' approaches, and consider them from the point of view expressed by Schroedinger. I also discuss how quantum entanglement, a nonclassical feature of quantum mechanics, can help to address the 'problem of small numbers' that led Schroedinger to promote the idea of a molecular code-script for explaining the stability of biological order. BioMed Central 2008-04-17 /pmc/articles/PMC2413215/ /pubmed/18419815 http://dx.doi.org/10.1186/1745-6150-3-15 Text en Copyright © 2008 Ogryzko; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Hypothesis Ogryzko, Vasily V Erwin Schroedinger, Francis Crick and epigenetic stability |
title | Erwin Schroedinger, Francis Crick and epigenetic stability |
title_full | Erwin Schroedinger, Francis Crick and epigenetic stability |
title_fullStr | Erwin Schroedinger, Francis Crick and epigenetic stability |
title_full_unstemmed | Erwin Schroedinger, Francis Crick and epigenetic stability |
title_short | Erwin Schroedinger, Francis Crick and epigenetic stability |
title_sort | erwin schroedinger, francis crick and epigenetic stability |
topic | Hypothesis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413215/ https://www.ncbi.nlm.nih.gov/pubmed/18419815 http://dx.doi.org/10.1186/1745-6150-3-15 |
work_keys_str_mv | AT ogryzkovasilyv erwinschroedingerfranciscrickandepigeneticstability |