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Barnase as a New Therapeutic Agent Triggering Apoptosis in Human Cancer Cells

BACKGROUND: RNases are currently studied as non-mutagenic alternatives to the harmful DNA-damaging anticancer drugs commonly used in clinical practice. Many mammalian RNases are not potent toxins due to the strong inhibition by ribonuclease inhibitor (RI) presented in the cytoplasm of mammalian cell...

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Detalles Bibliográficos
Autores principales:	Edelweiss, Evelina, Balandin, Taras G., Ivanova, Julia L., Lutsenko, Gennady V., Leonova, Olga G., Popenko, Vladimir I., Sapozhnikov, Alexander M., Deyev, Sergey M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413406/ https://www.ncbi.nlm.nih.gov/pubmed/18560598 http://dx.doi.org/10.1371/journal.pone.0002434

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