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Pooling serum samples may lead to loss of potential biomarkers in SELDI-ToF MS proteomic profiling

BACKGROUND: High throughput proteomic technology offers promise for the detection of disease biomarkers and proteomic signature patterns but biomarker discovery studies can be limited by cost factors when large sample size numbers are required. Pooling sera or plasma samples from disease cases poten...

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Detalles Bibliográficos
Autores principales: Sadiq, S Tariq, Agranoff, Dan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2414484/
https://www.ncbi.nlm.nih.gov/pubmed/18513446
http://dx.doi.org/10.1186/1477-5956-6-16