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Statistical Methods for Mapping Multiple QTL

Since Lander and Botstein proposed the interval mapping method for QTL mapping data analysis in 1989, tremendous progress has been made in the last many years to advance new and powerful statistical methods for QTL analysis. Recent research progress has been focused on statistical methods and issues...

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Detalles Bibliográficos
Autores principales: Zou, Wei, Zeng, Zhao-Bang
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423007/
https://www.ncbi.nlm.nih.gov/pubmed/18551187
http://dx.doi.org/10.1155/2008/286561
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author Zou, Wei
Zeng, Zhao-Bang
author_facet Zou, Wei
Zeng, Zhao-Bang
author_sort Zou, Wei
collection PubMed
description Since Lander and Botstein proposed the interval mapping method for QTL mapping data analysis in 1989, tremendous progress has been made in the last many years to advance new and powerful statistical methods for QTL analysis. Recent research progress has been focused on statistical methods and issues for mapping multiple QTL together. In this article, we review this progress. We focus the discussion on the statistical methods for mapping multiple QTL by maximum likelihood and Bayesian methods and also on determining appropriate thresholds for the analysis.
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spelling pubmed-24230072008-11-06 Statistical Methods for Mapping Multiple QTL Zou, Wei Zeng, Zhao-Bang Int J Plant Genomics Review Article Since Lander and Botstein proposed the interval mapping method for QTL mapping data analysis in 1989, tremendous progress has been made in the last many years to advance new and powerful statistical methods for QTL analysis. Recent research progress has been focused on statistical methods and issues for mapping multiple QTL together. In this article, we review this progress. We focus the discussion on the statistical methods for mapping multiple QTL by maximum likelihood and Bayesian methods and also on determining appropriate thresholds for the analysis. Hindawi Publishing Corporation 2008 2008-06-08 /pmc/articles/PMC2423007/ /pubmed/18551187 http://dx.doi.org/10.1155/2008/286561 Text en Copyright © 2008 W. Zou and Z.-B. Zeng. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Zou, Wei
Zeng, Zhao-Bang
Statistical Methods for Mapping Multiple QTL
title Statistical Methods for Mapping Multiple QTL
title_full Statistical Methods for Mapping Multiple QTL
title_fullStr Statistical Methods for Mapping Multiple QTL
title_full_unstemmed Statistical Methods for Mapping Multiple QTL
title_short Statistical Methods for Mapping Multiple QTL
title_sort statistical methods for mapping multiple qtl
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423007/
https://www.ncbi.nlm.nih.gov/pubmed/18551187
http://dx.doi.org/10.1155/2008/286561
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