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CUSP: an algorithm to distinguish structurally conserved and unconserved regions in protein domain alignments and its application in the study of large length variations
BACKGROUND: Distantly related proteins adopt and retain similar structural scaffolds despite length variations that could be as much as two-fold in some protein superfamilies. In this paper, we describe an analysis of indel regions that accommodate length variations amongst related proteins. We have...
Autores principales: | Sandhya, Sankaran, Pankaj, Barah, Govind, Madabosse Kande, Offmann, Bernard, Srinivasan, Narayanaswamy, Sowdhamini, Ramanathan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423364/ https://www.ncbi.nlm.nih.gov/pubmed/18513436 http://dx.doi.org/10.1186/1472-6807-8-28 |
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