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Identification and characterization of the human inhibitor of caspase-activated DNase gene promoter
DNA fragmentation factor is a heterodimer complex of the nuclease CAD and its specific inhibitor ICAD, which can be activated during apoptosis to induce DNA fragmentation. Although ICAD expression levels have been quantified in a variety of human cancer cells, the mechanism of ICAD gene regulation r...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423419/ https://www.ncbi.nlm.nih.gov/pubmed/18500556 http://dx.doi.org/10.1007/s10495-008-0223-8 |