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HyperISGylation of Old World Monkey ISG15 in Human Cells

BACKGROUND: ISG15 is an Ubiquitin-like protein, highly induced by Type I Interferons. Upon the cooperative activity of specific Ubiquitinating enzymes, ISG15 can be conjugated to its substrates. Increasing evidence points to a role for protein ISGylation in anti-viral and anti-tumoral defense. PRINC...

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Detalles Bibliográficos
Autores principales:	Pattyn, Els, Verhee, Annick, Uyttendaele, Isabel, Piessevaux, Julie, Timmerman, Evy, Gevaert, Kris, Vandekerckhove, Joël, Peelman, Frank, Tavernier, Jan
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423471/ https://www.ncbi.nlm.nih.gov/pubmed/18560560 http://dx.doi.org/10.1371/journal.pone.0002427

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