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Formin 1-Isoform IV Deficient Cells Exhibit Defects in Cell Spreading and Focal Adhesion Formation

BACKGROUND: Regulation of the cytoskeleton is a central feature of cell migration. The formin family of proteins controls the rate of actin nucleation at its barbed end. Thus, formins are predicted to contribute to several important cell processes such as locomotion, membrane ruffling, vesicle endoc...

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Detalles Bibliográficos
Autores principales: Dettenhofer, Markus, Zhou, Fen, Leder, Philip
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423616/
https://www.ncbi.nlm.nih.gov/pubmed/18560567
http://dx.doi.org/10.1371/journal.pone.0002497

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