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Recognition of Intrabiliary Hepatic Metastases From Colorectal Adenocarcinoma
Intrinsic involvement of bile ducts, by metastatic colorectal adenocarcinoma growing from within or invading the lumen of bile ducts, is not a well recognized pattern of tumor growth. Clinical, radiographic, operative, and histopathologic aspects of 15 patients with intrabiliary colorectal metastase...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424001/ https://www.ncbi.nlm.nih.gov/pubmed/10977117 http://dx.doi.org/10.1155/2000/17619 |
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author | Povoski, Stephen P. Klimstra, David S. Brown, Karen T. Schwartz, Lawrence H. Kurtz, Robert C. Jarnagin, William R. Fong, Yuman Blumgart, Leslie H. |
author_facet | Povoski, Stephen P. Klimstra, David S. Brown, Karen T. Schwartz, Lawrence H. Kurtz, Robert C. Jarnagin, William R. Fong, Yuman Blumgart, Leslie H. |
author_sort | Povoski, Stephen P. |
collection | PubMed |
description | Intrinsic involvement of bile ducts, by metastatic colorectal adenocarcinoma growing from within or invading the lumen of bile ducts, is not a well recognized pattern of tumor growth. Clinical, radiographic, operative, and histopathologic aspects of 15 patients with intrabiliary colorectal metastases were described. Fourteen patients were explored for possible hepatic resection. Two had jaundice, two radiographic evidence of an intrabiliary filling defect, 10 intraoperative evidence of intrabiliary tumor, and six microscopic evidence of intrabiliariy tumor. Eleven patients underwent hepatic resection. Five of the resected patients developed hepatic recurrence. Four patients were explored for possible repeat resection. One had jaundice, one radiographic evidence of an intrabiliary filling defect, all had intraoperative evidence of intrabiliary tumor, and three microscopic evidence of intrabiliary tumor. Three patients underwent repeat hepatic resection. All patients with preoperative jaundice and radiographic evidence of an intrabiliary filling defect were unresectable. Overall, actuarial five-year survival is 33% for those patients resected versus 0% for those not resected. Intraoperative recognition of intrabiliary tumor at exploration for hepatic resection was more common than clinical, radiographic, or histopathologic recognition. More diligent examination of resected liver tissue by the surgeon and pathologist may increase identification of bile duct involvement and aid in achieving adequate tumor clearance. |
format | Text |
id | pubmed-2424001 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2000 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-24240012008-07-08 Recognition of Intrabiliary Hepatic Metastases From Colorectal Adenocarcinoma Povoski, Stephen P. Klimstra, David S. Brown, Karen T. Schwartz, Lawrence H. Kurtz, Robert C. Jarnagin, William R. Fong, Yuman Blumgart, Leslie H. HPB Surg Research Article Intrinsic involvement of bile ducts, by metastatic colorectal adenocarcinoma growing from within or invading the lumen of bile ducts, is not a well recognized pattern of tumor growth. Clinical, radiographic, operative, and histopathologic aspects of 15 patients with intrabiliary colorectal metastases were described. Fourteen patients were explored for possible hepatic resection. Two had jaundice, two radiographic evidence of an intrabiliary filling defect, 10 intraoperative evidence of intrabiliary tumor, and six microscopic evidence of intrabiliariy tumor. Eleven patients underwent hepatic resection. Five of the resected patients developed hepatic recurrence. Four patients were explored for possible repeat resection. One had jaundice, one radiographic evidence of an intrabiliary filling defect, all had intraoperative evidence of intrabiliary tumor, and three microscopic evidence of intrabiliary tumor. Three patients underwent repeat hepatic resection. All patients with preoperative jaundice and radiographic evidence of an intrabiliary filling defect were unresectable. Overall, actuarial five-year survival is 33% for those patients resected versus 0% for those not resected. Intraoperative recognition of intrabiliary tumor at exploration for hepatic resection was more common than clinical, radiographic, or histopathologic recognition. More diligent examination of resected liver tissue by the surgeon and pathologist may increase identification of bile duct involvement and aid in achieving adequate tumor clearance. Hindawi Publishing Corporation 2000-08 /pmc/articles/PMC2424001/ /pubmed/10977117 http://dx.doi.org/10.1155/2000/17619 Text en Copyright © 2000 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Povoski, Stephen P. Klimstra, David S. Brown, Karen T. Schwartz, Lawrence H. Kurtz, Robert C. Jarnagin, William R. Fong, Yuman Blumgart, Leslie H. Recognition of Intrabiliary Hepatic Metastases From Colorectal Adenocarcinoma |
title | Recognition of Intrabiliary Hepatic Metastases
From Colorectal Adenocarcinoma |
title_full | Recognition of Intrabiliary Hepatic Metastases
From Colorectal Adenocarcinoma |
title_fullStr | Recognition of Intrabiliary Hepatic Metastases
From Colorectal Adenocarcinoma |
title_full_unstemmed | Recognition of Intrabiliary Hepatic Metastases
From Colorectal Adenocarcinoma |
title_short | Recognition of Intrabiliary Hepatic Metastases
From Colorectal Adenocarcinoma |
title_sort | recognition of intrabiliary hepatic metastases
from colorectal adenocarcinoma |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424001/ https://www.ncbi.nlm.nih.gov/pubmed/10977117 http://dx.doi.org/10.1155/2000/17619 |
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