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Improving the accuracy of template-based predictions by mixing and matching between initial models

BACKGROUND: Comparative modeling is a technique to predict the three dimensional structure of a given protein sequence based primarily on its alignment to one or more proteins with experimentally determined structures. A major bottleneck of current comparative modeling methods is the lack of methods...

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Detalles Bibliográficos
Autores principales: Liu, Tianyun, Guerquin, Michal, Samudrala, Ram
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424052/
https://www.ncbi.nlm.nih.gov/pubmed/18457597
http://dx.doi.org/10.1186/1472-6807-8-24