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Silencing of Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Responsive Cancer Cells

BACKGROUND: Keratinocyte growth factor receptor (KGFR) is a splice variant of the FGFR2 gene expressed in epithelial cells. Activation of KGFR is a key factor in the regulation of physiological processes in epithelial cells such as proliferation, differentiation and wound healing. Alterations of KGF...

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Detalles Bibliográficos
Autores principales: Rotolo, Sabrina, Ceccarelli, Simona, Romano, Ferdinando, Frati, Luigi, Marchese, Cinzia, Angeloni, Antonio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424182/
https://www.ncbi.nlm.nih.gov/pubmed/18575591
http://dx.doi.org/10.1371/journal.pone.0002528