Cargando…

Silencing of Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Responsive Cancer Cells

BACKGROUND: Keratinocyte growth factor receptor (KGFR) is a splice variant of the FGFR2 gene expressed in epithelial cells. Activation of KGFR is a key factor in the regulation of physiological processes in epithelial cells such as proliferation, differentiation and wound healing. Alterations of KGF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rotolo, Sabrina, Ceccarelli, Simona, Romano, Ferdinando, Frati, Luigi, Marchese, Cinzia, Angeloni, Antonio
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424182/ https://www.ncbi.nlm.nih.gov/pubmed/18575591 http://dx.doi.org/10.1371/journal.pone.0002528

Ejemplares similares

TNFα Modulates Fibroblast Growth Factor Receptor 2 Gene Expression through the pRB/E2F1 Pathway: Identification of a Non-Canonical E2F Binding Motif
por: D’Amici, Sirio, et al.
Publicado: (2013)

Potential Prognostic and Diagnostic Application of a Novel Monoclonal Antibody Against Keratinocyte Growth Factor Receptor
por: Ceccarelli, Simona, et al.
Publicado: (2014)

Neuropilin 1 Mediates Keratinocyte Growth Factor Signaling in Adipose-Derived Stem Cells: Potential Involvement in Adipogenesis
por: Ceccarelli, Simona, et al.
Publicado: (2018)

Topical KGF treatment as a therapeutic strategy for vaginal atrophy in a model of ovariectomized mice
por: Ceccarelli, Simona, et al.
Publicado: (2014)

Assessing the Impact of Polyethylene Nano/Microplastic Exposure on Human Vaginal Keratinocytes
por: Pontecorvi, Paola, et al.
Publicado: (2023)

Characterization of Human Vaginal Mucosa Cells for Autologous In Vitro Cultured Vaginal Tissue Transplantation in Patients with MRKH Syndrome
por: Nodale, Cristina, et al.
Publicado: (2014)

Gene Expression Profile of Patients with Mayer-Rokitansky-Küster-Hauser Syndrome: New Insights into the Potential Role of Developmental Pathways
por: Nodale, Cristina, et al.
Publicado: (2014)

MiR-200c sensitizes Olaparib-resistant ovarian cancer cells by targeting Neuropilin 1
por: Vescarelli, Enrica, et al.
Publicado: (2020)

Epigenetic silencing of SALL2 confers tamoxifen resistance in breast cancer
por: Ye, Liping, et al.
Publicado: (2019)

Epigenetic silencing of SALL2 confers tamoxifen resistance in breast cancer
por: Ye, Liping, et al.
Publicado: (2022)

Altered Expression of Candidate Genes in Mayer–Rokitansky–Küster–Hauser Syndrome May Influence Vaginal Keratinocytes Biology: A Focus on Protein Kinase X
por: Pontecorvi, Paola, et al.
Publicado: (2021)

Fibroblast Growth Factor Receptor-2 Expression in Thyroid Tumor Progression: Potential Diagnostic Application
por: Redler, Adriano, et al.
Publicado: (2013)

Tamoxifen resistance alters sensitivity to 5-fluorouracil in a subset of estrogen receptor-positive breast cancer
por: Watanabe, Takayuki, et al.
Publicado: (2021)

Restoration of keratinocytic phenotypes in autonomous trisomy-rescued cells
por: Tanuma-Takahashi, Akiko, et al.
Publicado: (2021)

Protective Effect of Pomegranate on Oxidative Stress and Inflammatory Response Induced by 5-Fluorouracil in Human Keratinocytes
por: Rapa, Shara Francesca, et al.
Publicado: (2021)

Uracil-tegafur and tamoxifen versus cyclophosphamide, methotrexate, fluorouracil, and tamoxifen in postoperative adjuvant therapy for stage I, II, or IIIA lymph node-positive breast cancer: a comparative study
por: Park, Y, et al.
Publicado: (2009)

Protective effects of resveratrol against 5-fluorouracil-induced oxidative stress and inflammatory responses in human keratinocytes
por: Chen, Shu, et al.
Publicado: (2021)

Immunomodulatory Effect of Adipose-Derived Stem Cells: The Cutting Edge of Clinical Application
por: Ceccarelli, Simona, et al.
Publicado: (2020)

Uracil-tegafur and tamoxifen vs cyclophosphamide, methotrexate, fluorouracil, and tamoxifen in post-operative adjuvant therapy for stage I, II, or IIIA lymph node-positive breast cancer: a comparative study
por: Park, Y, et al.
Publicado: (2009)

Disruption of the ER-α36-EGFR/HER2 Positive Regulatory Loops Restores Tamoxifen Sensitivity in Tamoxifen Resistance Breast Cancer Cells
por: Yin, Li, et al.
Publicado: (2014)

Tamoxifen-Induced Epigenetic Silencing of Oestrogen-Regulated Genes in Anti-Hormone Resistant Breast Cancer
por: Stone, Andrew, et al.
Publicado: (2012)

Silencing of syndecan-binding protein enhances the inhibitory effect of tamoxifen and increases cellular sensitivity to estrogen
por: Zhang, Jun, et al.
Publicado: (2018)

Efficacy of tamoxifen for the treatment of severe equine asthma
por: Mainguy‐Seers, Sophie, et al.
Publicado: (2018)

The Use of Human Adipose-Derived Stem Cells in the Treatment of Physiological and Pathological Vulvar Dystrophies
por: Giuseppina Onesti, Maria, et al.
Publicado: (2016)

Efficacy of 5-Fluorouracil in the Treatment of Pterygium
por: Shah, Sobia U, et al.
Publicado: (2021)

Anti-Inflammatory Effects of β-Cryptoxanthin on 5-Fluorouracil-Induced Cytokine Expression in Human Oral Mucosal Keratinocytes
por: Yamanobe, Hironaka, et al.
Publicado: (2023)

Notch3 Targeting: A Novel Weapon against Ovarian Cancer Stem Cells
por: Ceccarelli, Simona, et al.
Publicado: (2019)

Sex-Related Factors in Cardiovascular Complications Associated to COVID-19
por: Megiorni, Francesca, et al.
Publicado: (2021)

HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels
por: Puca, Francesca, et al.
Publicado: (2014)

Chemoresistance of colorectal cancer to 5-fluorouracil is associated with silencing of the BNIP3 gene through aberrant methylation
por: He, Jianming, et al.
Publicado: (2017)

TEAD1 Silencing Regulates Cell Proliferation and Resistance to 5-Fluorouracil in Cutaneous Squamous Cell Carcinoma
por: Wang, Ziyang, et al.
Publicado: (2022)

Efficacy of palifermin (keratinocyte growth factor-1) in the amelioration of oral mucositis
por: Sonis, Stephen T
Publicado: (2010)

Efficacy of keratinocyte growth factor (palifermin) for the treatment of caustic esophageal burns
por: NUMANOĞLU, KEMAL VARIM, et al.
Publicado: (2014)

IARC on tamoxifen.
Publicado: (1996)

Tamoxifen evolution
por: Howell, A., et al.
Publicado: (2023)

Response of Mouse Breast Cancer Cells to Anastrozole, Tamoxifen, and the Combination
por: Xanthopoulos, J. M., et al.
Publicado: (2005)

A Comparative Study of the Efficacy of Intralesional 5 Fluorouracil vs Combination of 5 Fluorouracil with Triamcinolone Acetonide in Keloids
por: Monteiro, Rochelle C, et al.
Publicado: (2022)

Fluorouracil/oxaliplatin/panitumumab: Lack of efficacy: case report
Publicado: (2022)

Silencing Livin improved the sensitivity of colon cancer cells to 5-fluorouracil by regulating crosstalk between apoptosis and autophagy
por: Liu, Shuai, et al.
Publicado: (2018)

Effect of Chlorhexidine Digluconate in Early Wound Healing of Human Gingival Tissues. A Histological, Immunohistochemical and Biomolecular Analysis
por: Pilloni, Andrea, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rg5mdu4q0gm39ba4jegm86q020