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Enhanced identification and biological validation of differential gene expression via Illumina whole-genome expression arrays through the use of the model-based background correction methodology

Despite the tremendous growth of microarray usage in scientific studies, there is a lack of standards for background correction methodologies, especially in single-color microarray platforms. Traditional background subtraction methods often generate negative signals and thus cause large amounts of d...

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Detalles Bibliográficos
Autores principales: Ding, Liang-Hao, Xie, Yang, Park, Seongmi, Xiao, Guanghua, Story, Michael D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425463/
https://www.ncbi.nlm.nih.gov/pubmed/18450815
http://dx.doi.org/10.1093/nar/gkn234