Cargando…

Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks

DNA nonhomologous end-joining (NHEJ) and homologous recombination are two distinct pathways of DNA double-strand break repair in mammalian cells. Biochemical and genetic studies showed that DNA ends can also be joined via microhomology-mediated end joining (MHEJ), especially when proteins responsibl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Li, Deng, Li, Nguyen, Son C., Zhao, Xin, Maulion, Christopher D., Shao, Changshun, Tischfield, Jay A.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425475/ https://www.ncbi.nlm.nih.gov/pubmed/18440984 http://dx.doi.org/10.1093/nar/gkn184

Ejemplares similares

Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms
por: Kostyrko, Kaja, et al.
Publicado: (2016)

Plant organellar DNA polymerases repair double-stranded breaks by microhomology-mediated end-joining
por: García-Medel, Paola L, et al.
Publicado: (2019)

Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions
por: Tadi, Satish Kumar, et al.
Publicado: (2016)

The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies
por: Mansour, Wael Y., et al.
Publicado: (2010)

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
por: Abdou, Ismail, et al.
Publicado: (2015)

Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining
por: Kukshal, Vandna, et al.
Publicado: (2015)

DNA Ligases I and III Cooperate in Alternative Non-Homologous End-Joining in Vertebrates
por: Paul, Katja, et al.
Publicado: (2013)

Comparative analysis of the end-joining activity of several DNA ligases
por: Bauer, Robert J., et al.
Publicado: (2017)

Microhomology Selection for Microhomology Mediated End Joining in Saccharomyces cerevisiae
por: Lee, Kihoon, et al.
Publicado: (2019)

Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks
por: Mansour, Wael Y., et al.
Publicado: (2008)

DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation
por: Simsek, Deniz, et al.
Publicado: (2011)

Saccharomyces cerevisiae DNA Ligase IV Supports Imprecise End Joining Independently of Its Catalytic Activity
por: Chiruvella, Kishore K., et al.
Publicado: (2013)

Mismatch discrimination and sequence bias during end-joining by DNA ligases
por: Bilotti, Katharina, et al.
Publicado: (2022)

RPA Antagonizes Microhomology-Mediated Repair of DNA Double-Strand Breaks
por: Deng, Sarah K, et al.
Publicado: (2014)

Loss of DNA ligase IV prevents recognition of DNA by double-strand break repair proteins XRCC4 and XLF
por: Jayaram, Sumithra, et al.
Publicado: (2008)

Mechanism of Microhomology-Mediated End-Joining Promoted by Human DNA Polymerase Theta
por: Kent, Tatiana, et al.
Publicado: (2015)

Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes
por: Glover, Lucy, et al.
Publicado: (2008)

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells
por: Pan-Hammarström, Qiang, et al.
Publicado: (2005)

Microhomology-mediated end joining: new players join the team
por: Wang, Hailong, et al.
Publicado: (2017)

Kinetic Characterization of Single Strand Break Ligation in Duplex DNA by T4 DNA Ligase
por: Lohman, Gregory J. S., et al.
Publicado: (2011)

Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining
por: Singer, Mirko, et al.
Publicado: (2015)

DNA Ligase IV and Artemis Act Cooperatively to Suppress Homologous Recombination in Human Cells: Implications for DNA Double-Strand Break Repair
por: Kurosawa, Aya, et al.
Publicado: (2013)

Telomere dynamics and fusion of critically shortened telomeres in plants lacking DNA ligase IV
por: Heacock, Michelle L., et al.
Publicado: (2007)

ZEB1 promotes non-homologous end joining double-strand break repair
por: Genetta, Thomas L, et al.
Publicado: (2023)

Structure of the Catalytic Region of DNA Ligase IV in Complex with an Artemis Fragment Sheds Light on Double-Strand Break Repair
por: Ochi, Takashi, et al.
Publicado: (2013)

Human DNA ligases I and III have stand-alone end-joining capability, but differ in ligation efficiency and specificity
por: McNally, Justin R, et al.
Publicado: (2023)

Polθ promotes the repair of 5′-DNA-protein crosslinks by microhomology-mediated end-joining
por: Chandramouly, Gurushankar, et al.
Publicado: (2021)

A mechanism for DNA-PK activation requiring unique contributions from each strand of a DNA terminus and implications for microhomology-mediated nonhomologous DNA end joining
por: Pawelczak, Katherine S., et al.
Publicado: (2008)

Microhomology-mediated end joining induces hypermutagenesis at breakpoint junctions
por: Sinha, Supriya, et al.
Publicado: (2017)

Distinct roles of XRCC4 and Ku80 in non-homologous end-joining of endonuclease- and ionizing radiation-induced DNA double-strand breaks
por: Schulte-Uentrop, Leonie, et al.
Publicado: (2008)

Real Estate in the DNA Damage Response: Ubiquitin and SUMO Ligases Home in on DNA Double-Strand Breaks
por: Dantuma, Nico P., et al.
Publicado: (2016)

Essential Factors for Incompatible DNA End Joining at Chromosomal DNA Double Strand Breaks In Vivo
por: Ogiwara, Hideaki, et al.
Publicado: (2011)

Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV–deficient B cells
por: Han, Li, et al.
Publicado: (2008)

Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV–deficient B cells
por: Han, Li, et al.
Publicado: (2008)

An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex
por: Hammel, Michal, et al.
Publicado: (2016)

Bacterial Ligase D preternary-precatalytic complex performs efficient abasic sites processing at double strand breaks during nonhomologous end joining
por: de Ory, Ana, et al.
Publicado: (2019)

Homology and enzymatic requirements of microhomology-dependent alternative end joining
por: Sharma, S, et al.
Publicado: (2015)

DNA ligase IV syndrome; a review
por: Altmann, Thomas, et al.
Publicado: (2016)

Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence
por: Gu, Jiafeng, et al.
Publicado: (2007)

Replication Stress Induces Micronuclei Comprising of Aggregated DNA Double-Strand Breaks
por: Xu, Bing, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_cks57srvapf25rdlakt4oigaoj