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Conserved residues in the δ subunit help the E. coli clamp loader, γ complex, target primer-template DNA for clamp assembly

The Escherichia coli clamp loader, γ complex (γ(3)δδ′λψ), catalyzes ATP-driven assembly of β clamps onto primer-template DNA (p/tDNA), enabling processive replication. The mechanism by which γ complex targets p/tDNA for clamp assembly is not resolved. According to previous studies, charged/polar ami...

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Detalles Bibliográficos
Autores principales:	Chen, Siying, Coman, Maria Magdalena, Sakato, Miho, O’Donnell, Michael, Hingorani, Manju M.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425476/ https://www.ncbi.nlm.nih.gov/pubmed/18424802 http://dx.doi.org/10.1093/nar/gkn157

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