Cargando…
Identification of a novel human Rad51 variant that promotes DNA strand exchange
Rad51 plays a key role in the repair of DNA double-strand breaks through homologous recombination, which is the central process in the maintenance of genomic integrity. Five paralogs of the human Rad51 gene (hRad51) have been identified to date, including hRad51B, hRad51C, hRad51D, Xrcc2 and Xrcc3....
Autores principales: | Park, Jung-Young, Yoo, Han-Wook, Kim, Bok-Ryang, Park, Raekil, Choi, Sang-Yun, Kim, Youngho |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425499/ https://www.ncbi.nlm.nih.gov/pubmed/18417535 http://dx.doi.org/10.1093/nar/gkn171 |
Ejemplares similares
-
Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities
por: Morozumi, Yuichi, et al.
Publicado: (2009) -
A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange
por: Shivji, Mahmud K. K., et al.
Publicado: (2006) -
Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching
por: Maki, Takahisa, et al.
Publicado: (2023) -
Stimulation of Dmc1-mediated DNA strand exchange by the human Rad54B protein
por: Sarai, Naoyuki, et al.
Publicado: (2006) -
RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51
por: Kovalenko, Oleg V., et al.
Publicado: (2006)