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Patients with rheumatoid arthritis have an altered circulatory aggrecan profile

BACKGROUND: Rheumatoid arthritis (RA) is a chronic auto-immune disease with extensive articular cartilage destruction. Aggrecan depletion, mediated by aggrecanases is one of the first signs of early cartilage erosion. We investigated, whether measurement of aggrecan and fragments thereof in serum, c...

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Detalles Bibliográficos
Autores principales:	Rousseau, Jean C, Sumer, Eren U, Hein, Gert, Sondergaard, Bodil C, Madsen, Suzi H, Pedersen, Christian, Neumann, Thomas, Mueller, Andreas, Qvist, Per, Delmas, Pierre, Karsdal, Morten A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426686/ https://www.ncbi.nlm.nih.gov/pubmed/18507823 http://dx.doi.org/10.1186/1471-2474-9-74

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