Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: Potent in vitro inhibitory activity against both R5- and X4-tropic HIV-1 strains without significant in vivo mucosal toxicity

BACKGROUND: Terpenoid derivatives originating from many plants species, are interesting compounds with numerous biological effects, such as anti-HIV-1 activity. The zinc tetra-ascorbo-camphorate complex (or "C14"), a new monoterpenoid derivative was evaluated in vitro for its anti-HIV-1 ac...

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Detalles Bibliográficos
Autores principales: Saïdi, Héla, Jenabian, Mohammad-Ali, Gombert, Bernard, Charpentier, Charlotte, Mannarini, Aurèle, Bélec, Laurent
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426711/
https://www.ncbi.nlm.nih.gov/pubmed/18522743
http://dx.doi.org/10.1186/1742-6405-5-10

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