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Highly diversified multiply drug-resistant HIV-1 quasispecies in PBMCs: a case report

BACKGROUND: Although drug resistance is a major challenge in HIV therapy, the effect of drug resistance mutations on HIV evolution in vivo is not well understood. We have now investigated genetic heterogeneity in HIV-1 by performing drug resistance genotyping of the PR-RT regions of viruses derived...

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Detalles Bibliográficos
Autores principales: Quan, Yudong, Brenner, Bluma G, Dascal, André, Wainberg, Mark A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426714/
https://www.ncbi.nlm.nih.gov/pubmed/18513421
http://dx.doi.org/10.1186/1742-4690-5-43