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Highly diversified multiply drug-resistant HIV-1 quasispecies in PBMCs: a case report
BACKGROUND: Although drug resistance is a major challenge in HIV therapy, the effect of drug resistance mutations on HIV evolution in vivo is not well understood. We have now investigated genetic heterogeneity in HIV-1 by performing drug resistance genotyping of the PR-RT regions of viruses derived...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426714/ https://www.ncbi.nlm.nih.gov/pubmed/18513421 http://dx.doi.org/10.1186/1742-4690-5-43 |