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The Role of the 14–20 Domain of the Islet Amyloid Polypeptide in Amyloid Formation
The molecular mechanism of amyloid formation by the islet amyloid polypeptide (IAPP) has been intensively studied since its identification in the late 1980s. The IAPP(20–29) region is considered to be the central amyloidogenic module of the polypeptide. This assumption is mainly based on the amyloid...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426739/ https://www.ncbi.nlm.nih.gov/pubmed/18566678 http://dx.doi.org/10.1155/2008/256954 |