Cargando…
Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores
Mps1 is an upstream component of the spindle assembly checkpoint, which, in human cells, is required for checkpoint activation in response to spindle damage but not apparently during an unperturbed mitosis. Mps1 also recruits Mad1 and Mad2 to kinetochores. However, whether the enzymatic activity of...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426934/ https://www.ncbi.nlm.nih.gov/pubmed/18541701 http://dx.doi.org/10.1083/jcb.200712028 |