Local Function Conservation in Sequence and Structure Space

We assess the variability of protein function in protein sequence and structure space. Various regions in this space exhibit considerable difference in the local conservation of molecular function. We analyze and capture local function conservation by means of logistic curves. Based on this analysis...

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Detalles Bibliográficos
Autores principales: Weinhold, Nils, Sander, Oliver, Domingues, Francisco S., Lengauer, Thomas, Sommer, Ingolf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427199/
https://www.ncbi.nlm.nih.gov/pubmed/18604264
http://dx.doi.org/10.1371/journal.pcbi.1000105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427199/
https://www.ncbi.nlm.nih.gov/pubmed/18604264
http://dx.doi.org/10.1371/journal.pcbi.1000105

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