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Local Function Conservation in Sequence and Structure Space
We assess the variability of protein function in protein sequence and structure space. Various regions in this space exhibit considerable difference in the local conservation of molecular function. We analyze and capture local function conservation by means of logistic curves. Based on this analysis...
Autores principales: | Weinhold, Nils, Sander, Oliver, Domingues, Francisco S., Lengauer, Thomas, Sommer, Ingolf |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427199/ https://www.ncbi.nlm.nih.gov/pubmed/18604264 http://dx.doi.org/10.1371/journal.pcbi.1000105 |
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